“Tick-borne affliction, informally” crossword clue

Reveal the answer to see why it works and where this clue has appeared before.LYME is the answer to the New York Times crossword clue “Tick-borne affliction, informally”. It was last seen in the puzzle of September 11, 2025, where it runs at 33 Across and fills 4 squares. It crosses 4 other entries in that grid — those are listed below and are the quickest way to confirm the letters you already have.