“Something legally defined in the U.S. as affecting fewer than 200,000 people” crossword clue

Reveal the answer to see why it works and where this clue has appeared before.RAREDISEASE is the answer to the New York Times crossword clue “Something legally defined in the U.S. as affecting fewer than 200,000 people”. It was last seen in the puzzle of March 15, 2025, where it runs at 18 Down and fills 11 squares. It crosses 11 other entries in that grid — those are listed below and are the quickest way to confirm the letters you already have.