“Prefix with center” crossword clue
Answer
E
P
I
•••EPI
Reveal the answer to see why it works and where this clue has appeared before.EPI is the answer to the New York Times crossword clue “Prefix with center”. It was last seen in the puzzle of April 21, 2026, where it runs at 3 Down and fills 3 squares. It crosses 3 other entries in that grid — those are listed below and are the quickest way to confirm the letters you already have.
Crossing entries
Apr 21, 2026 gridMore clues from this puzzle
Apr 21, 20267AWise thinker4 ltrs›11AForm of poetry Pablo Neruda used to praise socks, onions and salt3 ltrs›15ADo some farmwork4 ltrs›16A___ de plume3 ltrs›19AWhitney who invented the cotton gin3 ltrs›20ASoak up6 ltrs›21A"___ have to do"4 ltrs›22AGrifters' schemes4 ltrs›
Back to the full Apr 21, 2026 answer list, or browse the puzzle archive.