“Natural dividing line on a U.S. map, as suggested by this puzzle's circled letters” crossword clue

Reveal the answer to see why it works and where this clue has appeared before.MISSISSIPPI is the answer to the New York Times crossword clue “Natural dividing line on a U.S. map, as suggested by this puzzle's circled letters”. It was last seen in the puzzle of June 11, 2025, where it runs at 18 Down and fills 11 squares. It crosses 11 other entries in that grid — those are listed below and are the quickest way to confirm the letters you already have.