“Major research lab for astronauts, for short” crossword clue

Reveal the answer to see why it works and where this clue has appeared before.ISS is the answer to the New York Times crossword clue “Major research lab for astronauts, for short”. It was last seen in the puzzle of April 5, 2026, where it runs at 17 Down and fills 3 squares. It crosses 3 other entries in that grid — those are listed below and are the quickest way to confirm the letters you already have.