“Crucial difficulty to get through” crossword clue
Answer
I
S
I
S
••••ISIS
Reveal the answer to see why it works and where this clue has appeared before.ISIS is the answer to the New York Times crossword clue “Crucial difficulty to get through”. It was last seen in the puzzle of September 25, 2025, where it runs at 53 Down and fills 4 squares. It crosses 4 other entries in that grid — those are listed below and are the quickest way to confirm the letters you already have.
Crossing entries
Sep 25, 2025 grid52AWhat each Down answer needs from its clue in order to make sense15 ltrs›59ABig name in laptops4 ltrs›62ABeginning of every Washington State ZIP code4 ltrs›65ADisapproving sounds4 ltrs›
More clues from this puzzle
Sep 25, 20251AOnetime capital of the Mughal Empire4 ltrs›5ADad on "Family Guy"5 ltrs›10AWord after long or before paper4 ltrs›14AFilm unit4 ltrs›15A"Pardon me," in Padua5 ltrs›16AHome of Minor League Baseball's SeaWolves (more than 350 miles from the ocean!)4 ltrs›17AAirline known for tight security4 ltrs›18AContinental products5 ltrs›
Back to the full Sep 25, 2025 answer list, or browse the puzzle archive.